Intra-Cellular Therapies, Inc. announced the results from a Phase Ib/II clinical trial in patients with schizophrenia with ITI-007, the Company's unique, investigational new drug for the treatment of schizophrenia. The trial met its primary endpoint demonstrating that ITI-007 was safe and well-tolerated in patients with stabilized schizophrenia...

About 1 in 10 people have the potential to develop schizophrenia, but only 1 in 100 actually end up with this devastating illness. The challenge is in knowing why some do and some don't. Drawing from over 25 years of laboratory study, Mark F...

People with schizophrenia are more likely than others to sustain medical injuries during non-psychiatric hospital stays, a large national study finds...

Scientists are making progress towards a better understanding of the neuropathology associated with debilitating psychiatric illnesses like bipolar disorder and schizophrenia. New research, published by Cell Press in the July 15 issue of the journal Neuron, reveals mechanisms that connect a known psychiatric risk gene to disruptions in brain cell proliferation and migration during development...

Researchers at the University of Granada have designed a new training program on specific self-efficacy for reducing stress in psychotic patients. When stress was reduced, patients reported an improvement in symptoms, which meant enhancement of their well-being and quality of life. Researchers proved that these patients can improve their quality of life through proper psychological intervention...

People with mental health problems are committing fewer homicides while the number of suicides by mental health patients has also fallen, latest figures reveal; a previous rise in homicides by mentally ill people may have been the result of drug misuse, says the report...

Learning and memory impairments are important contributors to the disability associated with schizophrenia. These functional impairments emerge long before the onset of other symptoms associated with schizophrenia, suggesting that they are a consequence of a disturbance in brain development...

Dendritic spines act as hubs for communication between nerve cells. Reductions in spines may contribute to a lack of coordination in activity between brain regions. This structural abnormality is particularly relevant in schizophrenia, where pyramidal neurons located in layer 3, the principal cell type receiving communication from other brain regions, have fewer dendritic spines...

Schizophrenia is a heterogeneous disease, due to the fact that the reasons for its onset are varied, as are the reactions of patients who suffer from it. Some experts relieve that gender is an important factor in this heterogeneity...

For the first time, scientists have linked a brain compound called kynurenic acid to cognition, possibly opening doors for new ways to enhance memory function and treat catastrophic brain diseases, according to a new study from the University of Maryland School of Medicine...

The National Alliance on Mental Illness (NAMI) will screen the award-winning documentary, Unlisted: A Story of Schizophrenia, at its national convention in Washington, D.C. on July 2. Unlisted is scheduled for release to PBS stations in October 2010, coinciding with Mental Illness Awareness Week (MIAW)...

Many diseases of brain function, such as epilepsy and schizophrenia, are caused by problems in how neurons communicate with each other. A University of Houston (UH) researcher and his team are analyzing these commands and connections in an attempt to prevent those diseases. Dr. Jan-Ake Gustafsson, Robert A...

Schizophrenia, which is characterized by abnormalities in expression or perception of reality, is a mental illness that frequently consists of auditory hallucinations (hearing things that are not there), bizarre delusions, paranoid delusions, disorganized speech (in some types), disorganized thinking, and significant social or occupational dysfunction...

Paranoid schizophrenia is a schizophrenia subtype in which the patient has false beliefs (delusions) that somebody or some people are plotting against them or members of their family. People with paranoid schizophrenia, as with most subtypes may also have auditory hallucinations - they hear things that are not real...

Schizophrenia is a debilitating mental disorder affecting one in 100 people worldwide. Most cases aren't detected until a person starts experiencing symptoms like delusions and hallucinations as a teenager or adult. By that time, the disease has often progressed so far that it can be difficult to treat...

Disorganized schizophrenia, or hebephrenia (hebephrenic schizophrenia ) is one of several subtypes of schizophrenia, a chronic (long-term) mental illness - it is thought to be an extreme expression of disorganization syndrome that has been hypothesized to be one feature of a 3-factor model of schizophrenia symptoms; the others factors being delusions/hallucinations (reality dis...

Catatonic schizophrenia is a type (or subtype) of schizophrenia that includes extremes of behavior. At one end of the extreme the patient cannot speak, move or respond - there is a dramatic reduction in activity where virtually all movement stops, as in a catatonic stupor...

Childhood schizophrenia, also known as childhood-onset schizophrenia or early-onset schizophrenia is basically the same as schizophrenia in adults, but its onset occurs earlier in life. In some cases the patient may be ten years old, or even younger. Childhood schizophrenia can have a serious impact on the child's ability to function properly. Schizophrenia is a serious psychiatric illness...

Full-Service Partnerships (FSPs) are designed to do 'whatever it takes' to improve residential stability and mental health outcomes for homeless persons with serious mental illness. They are the cornerstone of California's Mental Health Services Act (MHSA) - one of the largest mental health policy experiments in recent history...

Veterans aged 55 years or older with PTSD (post-traumatic stress disorder) appear to have a higher risk of developing dementia over a 7-year period, compared to individuals without PTSD, says a new report published in Archives of Psychiatry today, a JAMA/Archives journal. PTSD occurs in a significant number of veterans returning from conflict areas or war zones, the article informs...