Authors: Kirchheiner J, Seeringer A, Viviani R More than fifty years of pharmacogenetic research have produced many examples of the impact of inherited variability in the response to psychotropic drugs. These successes, however, have as yet failed to translate into broadly applicable strategies for the improvement of individual drug treatment in psychiatry. One important argument against the widespread adoption of pharmacogenetics as a clinical tool is the lack of evidence showing its impact on medical decision making and on risk benefit ratio for the patients. The individual drug metabolizing capacity is assessed by genotyping drug metabolizing enzymes. The potential implications of information gained from genotyping are dose adjustments according to genotype. However, even when the c...MedWorm Message: Get the very latest Swine Flu news via the MedWorm Swine Flu RSS news feed - updated hourly from thousands of authoritative health and news sources.

Objectives:Older adults have high rates of suicide and typically seek care in primary medical practices. Older adults often do not directly or spontaneously report thoughts of suicide, which can impede suicide prevention efforts. Therefore, the use of addi... (Source: SafetyLit: All (Unduplicated))

The objective of this study was to investigate the influence of physical exercise on depressive symptoms and functional fitness in a sample of elderly people enrolled in a physical exercise program run by public sector Health Centers in Flori... (Source: SafetyLit: All (Unduplicated))

This study retrospectively investigated 4571 death examinations and autopsies that were performed at The Konya Branch of the Forensic Medici... (Source: SafetyLit: All (Unduplicated))

This review discusses the limitation of access to suicide methods as a way to prevent suicide, an approach which forms a major component of many national suicide prevention strategies. An important distinction is made between efforts that attempt to limit ... (Source: SafetyLit: All (Unduplicated))

Comment: Research showing that restricting access to barbecue charcoal is helpful in lowering the number of suicides has been welcomed by experts on suicide prevention. Language: Eng... (Source: SafetyLit: All (Unduplicated))MedWorm Message: Get the very latest Swine Flu news via the MedWorm Swine Flu RSS news feed - updated hourly from thousands of authoritative health and news sources.

BACKGROUND: Recent reports have suggested a pathophysiological role for brain-derived neurotrophic factor (BDNF) in major depression and suicide. We evaluate BDNF mRNA in peripheral blood mononuclear cells (PBMCs) of patients with major depression who had ... (Source: SafetyLit: All (Unduplicated))

BACKGROUND: Suicide is a complex and multifactorial phenomenon. The number of work-related suicides is difficult to assess in France. There are nevertheless some data available to document this problem. The aim of this study is to describe suicide attempts... (Source: SafetyLit: All (Unduplicated))

BACKGROUND/PURPOSE: Suicide is an important public health problem and one of the leading causes of death worldwide. The present study investigated the prevalence of suicidal ideation (SI) and its associated risk factors in the general population. METHODS: ... (Source: SafetyLit: All (Unduplicated))

BACKGROUND: In previous studies, some features of suicidal firearm deaths have been described, but series of suicidal deaths using shotgun are limited in the literature. The aim of the present study was to define several characteristics of suicidal shotgun... (Source: SafetyLit: All (Unduplicated))

Self-injury is a dangerous behavior that is different from suicidal behavior but is associated with increased risk of suicide attempts. Some effective psychological treatments for self-injury exist. Physicians in family medicine and primary care settings p... (Source: SafetyLit: All (Unduplicated))MedWorm Message: Get the very latest Swine Flu news via the MedWorm Swine Flu RSS news feed - updated hourly from thousands of authoritative health and news sources.

OBJECTIVE: We explored differences between high and low-impulsive incarcerated individuals in the context of lifetime self-mutilation, suicide ideation and suicide attempt. METHODS: A total of 1265 males detained in Italian penitentiary institutions were s... (Source: SafetyLit: All (Unduplicated))

BACKGROUND: Suicidal ideation (SID) is a major risk factor for suicide attempts. Mental disorders are among the strongest correlates of suicide, with depression and anxiety disorders playing a major role. The present study aims to investigate the contribut... (Source: SafetyLit: All (Unduplicated))

Everyone has been there. You are about to get into an accident, your heart races, your mind is completely focused on the oncoming car, time seems to slow, your thoughts become crystal clear. It's a near-death experience that you never forget. Your "stress response" has helped you to survive.Here's another scenario: your boss is shouting at you, your kids are sick, bills are piling up, life is getting really stressful on a chronic basis, day after day, and... after a while, you can't think straight! Your mind is racing, you have trouble paying attention and focusing, memory is impaired, worries abound, you can't make decisions or you make bad decisions, and depression may set in. Now the "stress response" is impairing your brain.What's going on here??Let's go back to basic biology. Long ago...

Coronation Street actress Beverley Callard reveals she has been receiving treatment for depression. (Source: BBC News | Health | UK Edition)

(Source: BMJ Online First)MedWorm Message: Get the very latest Swine Flu news via the MedWorm Swine Flu RSS news feed - updated hourly from thousands of authoritative health and news sources.

Abdominal compartment syndrome can result in depressed renal function, cardiac output, respiratory mechanics, and mesenteric perfusion. Which outcomes improve with VAC? Critical Care (Source: Medscape Today Headlines)

A new randomized trial shows that on average, three months after receiving a series of 10 massage sessions, patients had half the symptoms of anxiety. This improvement resembles that previously reported with psychotherapy, medications, or both. But the trial, published in the journal Depression and Anxiety, also found massage to be no more effective than simple relaxation in a room alone with soft, soothing music. "We were surprised to find that the benefits of massage were no greater than those of the same number of sessions of 'thermotherapy' or listening to relaxing music," said Karen J... (Source: Health News from Medical News Today)

In this study, the investigators examined HA as a potential mediator of treatment response to a serotonergic tricyclic antidepressant... (Source: Health News from Medical News Today)

Researchers at MIT are eagerly anticipating the summer delivery of Elekta Neuromag®, a system that uses magnetoencephalography or MEG to explore brain function. MEG can detect the very weak magnetic fields arising from electrical activity in the brain, and allows researchers to monitor the timing of brain activity with millisecond precision. MIT researchers will use MEG to study normal cognition in children and adults, as well as the neural basis of autism, depression, schizophrenia and other brain disorders... (Source: Health News from Medical News Today)